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Biotech Targeting Alzheimer's Disease Advances Toward Phase 1

Source:

Having secured a manufacturing partner for its proprietary antibody candidate, this precision medicine company charts progress toward a Phase 1 trial in Alzheimer's disease.

ProMIS Neurosciences Inc. (PMN:TSX; ARFXF:OTCQB), in a June 12 press release, announced "the initiation of producer cell line development for PMN310, its lead therapeutic antibody candidate for treatment of Alzheimer's disease." Selexis SA, called a "global leader in mammalian (suspension-adapted CHO-K1) cell line generation," has signed on to manufacture the therapeutic.

Phase 1 clinical trials for PMN310 are slated to begin in the second half of 2019, according to the announcement. The drug targets toxic oligomers, which ProMIS calls a "root cause" of Alzheimer's disease.

ProMIS President and CEO Dr. Elliot Goldstein stated the company had "recently completed successful affinity maturation of PMN310, which in addition to its unique and highly selective binding profile offers increased opportunity for best in class therapy for Alzheimer's disease."

Both Goldstein and Selexis vice president Yemi Onakunle highlighted the synergy between the two companies' products. "We believe our best-in-class technology can help propel forward this best-in-class therapeutic candidate," Onakunle stated in the release.

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Disclosure:
1) Tracy Salcedo compiled this article for Streetwise Reports LLC and provides services to Streetwise reports as an independent contractor. She or members of her household own securities of the following companies mentioned in the article: None. She or members of her household are paid by the following companies mentioned in this article: None.
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