Sunesis Pharmaceuticals Inc.

Sunesis Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of new oncology therapeutics for the treatment of solid and hematologic cancers. The company has built a highly experienced cancer drug development organization committed to advancing its lead product candidate, vosaroxin, in multiple indications to improve the lives of people with cancer.

Expert Comments:

Maxim Jacobs, Edison Investment Research (3/15/17)
"Sunesis Pharmaceuticals Inc.'s application for EU approval for vosaroxin in AML continues to progress. . .we continue to expect a launch in H2/17. . .the company plans to initiate a Phase Ib/II study of SNS-062, their BTK inhibitor, in patients with various advanced B-cell malignancies in H1/17. . .we have increased our valuation slightly to $219m or $10.47 per basic share."

Maxim Jacobs, Edison Investment Research (2/16/17)
"Sunesis Pharmaceuticals Inc. is advancing its clinical asset, SNS-062, a novel non-covalent, oral Bruton's tyrosine kinase inhibitor that may work in Imbruvica-relapsed and -refractory patients. Data from a Phase 1a study in healthy volunteers was recently presented and indicated an attractive pharmacokinetic/pharmacodynamic profile with twice a day dosing; a Phase 1b/2 is expected to begin in H1/17."

Jim Birchenough, Wells Fargo Securities (1/31/17)
"Wells Fargo Securities biotechnology team hosted Sunesis Pharmaceuticals Inc. on a non-deal roadshow with investors. . .with regards to QINPREZO, SNSS appears increasingly confident in prospects for approval following review of 180-day question from the European Medicines Agency and expects to submit a final response in March with Scientific review in April and a decision by late April/May. . .we are reiterating our OUTPERFORM rating. . .with potential approval of QINPREZO, high value partnership to eliminate the balance sheet risk, and potential blockbuster opportunity with SNS062, we believe that SNSS is undervalued relative to this opportunity and would be buyers here."

Zacks Equity Research (1/23/17)
"Sunesis Pharmaceuticals Inc. loss estimates narrowed 5.06% and 8.80% for 2017 and 2018, respectively, over the past 60 days. The company recorded a positive earnings surprise in three of the last four quarters, the average being 0.54%."

Maxim Jacobs, Edison Investment Research (12/13/16)
"Sunesis Pharmaceuticals Inc. reported new data on SNS-062 and Qinprezo at the American Society of Hematology meeting in December 2016. The Phase Ia trial of SNS-062 was completed and the company reported positive food effect data as well as an expanded safety data set without significant adverse events. . .The company also presented additional follow-up data from the patients on the Phase III VALOR trial in AML, which showed a durable survival benefit in patients over 60. . .We believe this strengthens the application package for EMA approval in spring 2017."

Maxim Jacobs, Edison Investment Research (12/8/16)
"Sunesis Pharmaceuticals Inc. is a pharmaceutical company developing small molecule oncology drugs; its leadprogram is Qinprezo, a quinolone derivative for relapsed/refractory acute myeloid leukemia (AML) without the dose limiting cardiotoxicity of anthracyclines. The FDA discouraged submitting an NDA after it missed its primary endpoint, but significant potential remains in Europe where Qinprezo has data comparable to those used in other related approvals. . .data from an SNS-062 Phase Ia study in healthy volunteers was recently presented and indicated an attractive PK/PD profile with twice a day dosing; a Phase I/IIa is expected to begin around year-end."

More Expert Comments

Experts Following This Company

Jim Birchenough – BMO Capital Markets
Maxim Jacobs – Edison Investment Research
Hartaj Singh, Biotechnology Analyst – BTIG Research
George Zavoico, Senior Equity Analyst – JonesTrading

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Investing Highlights
Totality of VALOR data shows compelling risk-benefit trade-off in disease with significant unmet need
Relapsed/refractory AML is a significant commercial opportunity with no approved agents
Sunesis Pharmaceuticals Inc. Content