RVX:TSX

Resverlogix Corp.

Resverlogix Corp. is developing RVX-208, a first-in-class, small molecule selective BET bromodomain inhibitor for the potential treatment of patients with cardiovascular disease, diabetes mellitus, Alzheimer's disease, peripheral artery disease and chronic kidney disease. RVX-208 is the only selective BET bromodomain inhibitor in clinical trials. The company's common shares trade on the Toronto Stock Exchange (TSX: RVX). For further information please visit www.resverlogix.com. Resverlogix can be followed on its blog at http://www.resverlogix.com/blog and via Twitter https://twitter.com/resverlogix_rvx @Resverlogix_RVX
RVX:TSX

Expert Comments:

Marcel Wijma, Van Leeuwenhoeck Research (5/1/17)
"Resverlogix Corp. is developing small molecules that selectively inhibit Bromodomain and Extra Terminal domain (BET) proteins, a new and emerging target for high risk vascular diseases. The company is the first to test the BET inhibition hypothesis as a new approach for reducing major adverse cardiovascular events (MACE) in high risk diabetes and CKD patients. . .we have increased our valuation based on an estimated higher pricing for apabetalone and expanded markets in high risk CKD patients. . .RVX remains gravely undervalued at the current share price of CAD 1.99. We feel that the company's current total value should be CAD $12.50 per share.

John Vandermosten, Zacks Equity Research (3/30/17)
"Resverlogix Corp.'s lead product candidate, apabetalone, is the first selective BET bromodomain inhibitor in clinical trials for high-risk vascular disease. In the current Phase III BETonMACE trial, apabetalone is targeting a very specific patient population with low HDL, type 2 diabetes mellitus and chronic kidney disease with a high cardiovascular risk for increased MACE. . .our investment thesis for Resverlogix is based on a large and growing underserved market in cardiovascular disease. With a growing older population in the world, and in many cases a less healthy one than in previous generations, the addressable market for therapies that reduce cardiovascular risk is increasing. "

John Vandermosten, Zacks Equity Research (12/16/16)
"Resverlogix Corp.'s lead product candidate, apabetalone, is the first selective BET bromodomain inhibitor in clinical trials for high-risk vascular disease. In the current Phase 3 BETonMACE trial, Apabetalone is targeting a very specific patient population with low HDL, type 2 diabetes mellitus and chronic kidney disease with a high cardiovascular risk for increased MACE. . .all planned countries including Argentina, Belgium, Bulgaria, Croatia, Germany, Hungary, Israel, Mexico, Poland, Serbia, and Slovakia have received regulatory approval to open clinical investigator sites and are recruiting patients and sites in Taiwan, China and Russia are expected to launch soon."

John Vandermosten, Zacks Equity Research (10/17/16)
"On October 13, 2016 Resverlogix Corp. held a research and development update for shareholders, investors and analysts in New York City. Several key opinion leaders and Resverlogix management team members spoke at the event providing an update on the latest thoughts on diabetes, chronic kidney disease and how these co-morbidities impact cardiovascular disease. . .we found the R&D update and KOL presentation very helpful in providing further understanding to the investment community of the opportunity for apabetalone and the company's epigenetic pipeline. Resverlogix has identified six different pathways where apabetalone has shown promise in improving MACE."

John Vandermosten, Zacks Equity Research (9/22/16)
"Resverlogix Corp. has increased the pace of investment into its portfolio of indications for apabetalone in recent quarters, launching a Phase 1 PK study with patients suffering from severe renal impairment and accelerating the pace of its BETonMACE study. We anticipate that the company will continue to launch studies in other neighboring indications as funding permits. . .we believe that durable patent position and the forecasted pricing of apabetalone, combined with a management skill set surrounding CVD and diabetes and a novel approach to addressing the residual risk in high need CVD patients, support our price target."

John Vandermosten, Zacks Equity Research (7/29/16)
"Resverlogix Corp.'s lead product candidate, apabetalone, is the first selective BET bromodomain inhibitor in clinical trials for high-risk vascular disease. In the current Phase 3 BETonMACE trial, Apabetalone is targeting a very specific patient population with low HDL, type diabetes mellitus and chronic kidney disease with a high cardiovascular risk for increased MACE. . .Resverlogix is based on a large and growing underserved market in cardiovascular disease. With a growing older population in the world. . .the addressable market for therapies that reduce cardiovascular risk is increasing. . .we believe the company is undervalued."

More Expert Comments

Experts Following This Company

John Vandermosten, CFA – Zacks Small-Cap Research
Marcel Wijma, Analyst – The Daily Molecule (Van Leeuwenhoeck Research), Van Leeuwenhoeck Research

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Investing Highlights
 
Phase III company focused on high-risk CVD population with lead therapeutic - apabetalone
 
Market leader with significant potential – Over 10MM patients in top 7 markets
 
Advancing apabetalone – Phase II CKD trial expected to commence in early 2017